AACN : PCCN Questions & Answers

Last Updated: Aug 29, 2026

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AACN PCCN Exam Syllabus Topics:

SectionWeightObjectives
Endocrine/Hematology/Neurology/Gastrointestinal/Renal24%- Renal
  • 1. CRRT/Dialysis
  • 2. Acute kidney injury
  • 3. Electrolyte imbalances
- Neurology
  • 1. Stroke management
  • 2. Traumatic brain injury
  • 3. Increased intracranial pressure
  • 4. Seizures and status epilepticus
- Endocrine
  • 1. Adrenal crisis
  • 2. Thyroid disorders
  • 3. Diabetic emergencies (DKA, HHS)
- Gastrointestinal
  • 1. GI bleeding
  • 2. Acute pancreatitis
  • 3. Liver failure
- Hematology
  • 1. Blood product administration
  • 2. Sickle cell crisis
  • 3. DIC (Disseminated Intravascular Coagulation)
Pulmonary21%- Acute Respiratory Failure
  • 1. ARDS
  • 2. Non-invasive ventilation (BiPAP/CPAP)
  • 3. Mechanical ventilation management
- Chronic Respiratory Disorders
  • 1. COPD exacerbation
  • 2. Asthma management
- Pulmonary Embolism
  • 1. Anticoagulation therapy
  • 2. Diagnosis and treatment
- Respiratory Assessment
  • 1. Pulse oximetry
  • 2. ABG interpretation
  • 3. Chest tube management
- Pneumonia
  • 1. Ventilator-associated
  • 2. Community-acquired
Multisystem22%- Trauma
  • 1. Trauma assessment and management
  • 2. Burns
- Shock
  • 1. Cardiogenic shock
  • 2. Septic shock
  • 3. Distributive shock
  • 4. Hypovolemic shock
- Post-operative Care
  • 1. Pain management
  • 2. Complications management
- Palliative/End-of-Life Care
  • 1. Symptom management
  • 2. Goals of care
  • 3. Ethical considerations
- Multiorgan Dysfunction Syndrome
  • 1. Management strategies
  • 2. Pathophysiology
- Sepsis
  • 1. Early recognition and bundles
  • 2. Organ dysfunction
Cardiovascular33%- Heart Failure
  • 1. Acute and chronic HF
  • 2. Left vs right heart failure
  • 3. Pharmacological management
- Vascular Disorders
  • 1. Peripheral vascular disease
  • 2. Aortic emergencies
- Acute Coronary Syndromes
  • 1. STEMI/NSTEMI management
  • 2. Cardiac biomarkers
  • 3. Unstable angina
- Dysrhythmias
  • 1. Cardioversion and defibrillation
  • 2. Pacemakers and ICDs
  • 3. Identification and management
- Hemodynamic Monitoring
  • 1. Arterial lines
  • 2. Cardiac output monitoring
  • 3. Central venous pressure
- Structural Heart Disease
  • 1. Cardiomyopathies
  • 2. Valvular disorders
  • 3. Pericardial disease

AACN Progressive Care Certified Nursing Sample Questions:

1. Which of the following is a cardiac hormone that regulates cardiovascular homeostasis and fluid volume during states of volume and pressure overload?

A) Nitroprusside
B) Octreotide
C) Hydralazine
D) Nesiritide


2. Cells in the which of the following have automaticity and can function as a backup pacemaker if all other pacemakers fail?

A) Left bundle branch
B) Right bundle branch
C) Bundle of His
D) Purkinje system


3. Which of the following statements is true related to the principle of double effect?

A) It attests that inadequate pain management in palliative care patients is illegal
B) It states that the administration of medications that may inadvertently hasten death is illegal
C) It asserts that a provider who assists in a patient's death cannot be legally charged
D) It helps to distinguish palliative care from assisted suicide


4. Which of the following statements is true regarding positive end-expiratory pressure (PEEP)?

A) Use of PEEP may decrease the risk of barotrauma due to lower mean and peak airway pressures during ventilation
B) PEEP may decrease intracranial pressure and increase renal perfusion
C) PEEP may decrease hepatic congestion
D) The application of positive pressure to the airways during expiration may keep alveoli open and prevent early closure during exhalation in conjunction with any of the ventilator modes


5. Following intravenous administration of which of the following angiotensin-converting enzyme (ACE) inhibitors does blood pressure lowering occur within 15 minutes and last from 4 to 6 hours?

A) Enalapril
B) Ramipril
C) Fosinopril
D) Captopril


Solutions:

Question # 1
Answer: D
Question # 2
Answer: D
Question # 3
Answer: D
Question # 4
Answer: D
Question # 5
Answer: A

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