American Society of Microbiology : ABMM Questions & Answers

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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

Question 1

A patient with a history of chronic obstructive pulmonary disease (COPD) experiences an acute exacerbation.
Sputum culture grows numerous Gram-negative coccobacilli that are oxidase-positive and grow on chocolate agar but not on sheep blood agar. The MOST likely organism is:

A. Moraxella catarrhalis
B. Streptococcus pneumoniae
C. Legionella pneumophila
D. Haemophilus influenzae

Question 2

Staphylococcus epidermidis, a common cause of healthcare-associated infections, forms biofilms on medical devices. The production of polysaccharide intercellular adhesin (PIA) is a key factor in biofilm maturation.
The expression of PIA is primarily regulated by:

A. Horizontal gene transfer of the ica operon.
B. A two-component regulatory system involving AgrA and AgrC.
C. The stringent response pathway activated during nutrient limitation.
D. The icaADBC operon, whose expression is influenced by environmental cues.

Question 3

A microbiology laboratory receives a cerebrospinal fluid (CSF) sample from a patient with suspected meningitis. Gram stain shows numerous Gram-negative diplococci. The organism grows on chocolate agar but not on blood agar without added CO2. The MOST likely identification is:

A. Listeria monocytogenes
B. Streptococcus pneumoniae
C. Neisseria meningitidis
D. Haemophilus influenzae

Question 4

A patient develops a localized skin infection characterized by a painless, progressive ulcer with raised, indurated margins. Microscopic examination of tissue scrapings reveals amastigotes within macrophages. The patient reports recent travel to Central or South America. The MOST likely diagnosis is cutaneous:

A. Leishmaniasis
B. Sporotrichosis
C. Myiasis
D. Chromoblastomycosis

Question 5

A clinical microbiology laboratory is investigating a cluster of bloodstream infections caused by Staphylococcus aureus. To differentiate between community-associated (CA-MRSA) and healthcare- associated (HA-MRSA) strains, they may look for the presence of:

A. Panton-Valentine leukocidin (PVL) toxin genes, which are exclusively found in HA-MRSA.
B. Specific staphylococcal cassette chromosome mec (SCCmec) types, such as SCCmec IV or V inCA- MRSA.
C. Resistance to non-beta-lactam antibiotics, which is more common in CA-MRSA.
D. The mecA gene, which is common to both CA-MRSA and HA-MRSA.

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