Nursing : ACNS Questions & Answers

Updated: Aug 09, 2026

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Nursing ACNS Exam Syllabus Topics:

SectionWeightObjectives
Clinical Expertise in Adult Health40-50%- Pathophysiology and Clinical Management
- Health Assessment and Promotion
- Therapeutic Interventions and Treatments
- Pharmacology for Adult Populations
- Acute and Chronic Disease Management
- Diagnostics and Laboratory Interpretation
Leadership and Consultation15-20%- Change Management and Innovation
- Quality Improvement and Patient Safety
- Healthcare Leadership Principles
- Consultation and Collaboration Skills
- Interprofessional Team Collaboration
Foundations of Advanced Practice8-12%- Healthcare Policy and Advocacy
- Advanced Practice Role Development
- Evidence-Based Practice Principles
- Professional Ethics and Legal Issues
- Theoretical Foundations of Nursing
Systems and Outcomes10-15%- Regulatory Compliance and Standards
- Healthcare Delivery Systems
- Healthcare Informatics and Technology
- Risk Management and Quality Assurance
- Resource Management and Cost-Effectiveness
Education and Research10-15%- Data Analysis and Outcome Measurement
- Clinical Scholarship and Publication
- Patient and Staff Education
- Research Utilization and Evidence Appraisal

Nursing ANCC Adult Health Clinical Nurse Specialist Certification (ACNS) Sample Questions:

1. When counseling a patient on side effects of her medication, a question comes up. What is the best way to manage and alleviate a common side effect of trazodone?

A) Take this medication in the morning
B) Eat more fiber while on this medication.
C) Take this medication at bedtime.
D) Drink a big glass of water with each dose.


2. How far should the external bumper of a PEG be from the abdominal wall?

A) 1 or 2 mm.
B) 3 or 4 mm.
C) 1 or 2 cm.
D) 3 or 4 cm


3. The 2003 IOM Patient Safety Report describes an electronic medical record as encompassing all of the following except:

A) a longitudinal collection of electronic health information
B) a cost-efficient means of documentation for the healthcare provider
C) immediate electronic access to a person's medical data by authorized users
D) support for efficient provision processes in health care


4. Most states require advanced practice nurses to have which type of work environment?

A) Collaborative.
B) Adjusted.
C) Traditional.
D) Independent.


5. You are conducting an abdominal assessment on a patient. During palpation, the patient complains that she is experiencing pain when you release pressure, though not during the palpation itself. This is known as what?

A) Quadrant pain.
B) Release pain.
C) Phantom pain.
D) Rebound pain.


Solutions:

Question # 1
Answer: C
Question # 2
Answer: C
Question # 3
Answer: B
Question # 4
Answer: A
Question # 5
Answer: D

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